• Jobs
  • Startups
  • Hire
LoginSign up

Role description

Future Opportunities

Matterworks logoMatterworks
TypeFull-time
WorkplaceHybrid
LocationSomerville, MA
Posted4/3/2025
Other

About Us

Most of the molecules driving human biology are invisible to us. Mass spectrometers already detect metabolites, lipids, and peptides, but the vast majority of those signals never get identified. A typical experiment names a small fraction of its features and discards the rest. We call this biology's dark matter. It’s signal-rich and mechanism-defining, yet almost entirely opaque.

Matterworks is building the foundation models that make that dark matter legible. Our Large Spectral Models do for biochemical biology what AlphaFold and ESM did for proteins: turning a library-bound discipline into something predictable and generative, and embedding it at every stage of R&D.

Come build the future of biological discovery with us.

If what you've seen, heard, read about Matterworks has sparked your interest, we'd love to hear from you!

We have exciting plans for the future of Matterworks. As we work toward achieving our goals and advancing our mission, we'll be expanding our team to support the effort. While we may not have an open role that aligns with your skills and interests at the moment, opportunities may be on the horizon.

Working at Matterworks

Given the cross-disciplinary and innovative nature of our work, effective collaboration and communication are critical to our progress. We operate in a flexible hybrid model that accommodates both fully remote team members and those who work full-time from our Somerville, MA office. While some positions may require regular in-person presence for hands-on work or local collaboration, many roles can be performed remotely with team members distributed across various locations.

Compensation and Benefits

Matterworks offers full-time employees a competitive base salary, stock options, and benefits (health & dental, vision, long- and short-term disability, life insurance, 401k with company match). Employees enjoy a flexible work & unlimited time away policy, commuter benefits and parking, regular team meals and outings, and company support for continued education/coursework and conference participation.

Matterworks, Inc. is an equal opportunity employer. All candidates for employment at Matterworks are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other category protected by law.

Relevant archetypes

Apply on Ashby
Save

Company info

Matterworks logo

Matterworks

The Predictive Biology Company

Biology has always been an empirical science. We're making it a science of prediction. Matterworks builds foundation models for biochemical omics — the next frontier in AI-powered research. Our platform, Pyxis, applies large-scale spectral modeling to mass spectrometry data, giving pharma and biotech teams the power to predict biological properties, classify disease states, and anticipate outcomes across the entire R&D lifecycle. From self-service exploration to lab services and enterprise partnerships, we work with pharma and biotech organizations to bring predictive biology to every stage of R&D.

Private companySeries A
HQSomerville, United States
Size51–200 employees
Unlock human wisdom
ThesisTermsPrivacy
Industry
Biotechnology Research
Funding
  • Series A · Jun 3, 2025
Investors
Germin8 VenturesIntermountain VenturesLewis & Clark CapitalOMX VenturesPillar VC

Claim matterworks.ai

Work at matterworks.ai? Sign in to claim this org and manage its profile.

© 2026 Saywise Inc.