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Role description

Mechanical Engineer, Fluidics/Perfusion

Until logoUntil
Zero to one
TypeFull-time
WorkplaceOn-site
SeniorityMid-level
Salary$120,000–$200,000
LocationSan Francisco, CA
Posted8/13/2025
Engineering

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

About You

  • Track record of exceptional engineering abilities
  • Deep understanding of heat and mass transfer principles
  • Experience designing fluidic systems for perfusion/heat exchangers
  • High degree of autonomy across full engineering stack: electromechanical design and fabrication, control software, physical modeling
  • Desire to join a fast-paced, scrappy engineering team

Preferred Qualifications

  • 3+ years experience/graduate level in Mechanical Engineering, Physics, or equivalent
  • Experience with organ perfusion in a research or clinical context
  • Experience working in a startup

Benefits

  • Opportunity for outsized impact creating the future as an early team member
  • Generous medical, dental and vision insurance coverage for employees and their dependents
  • Flexible time off and paid holidays
  • Competitive compensation package, including salary and equity
  • Access to a 401(k) retirement savings plan
  • FSA and commuter benefits
  • Subsidized lunch daily

As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.

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Company info

Until logo

Until

Pressing pause on biological time, for those who need it most.

We are building reversible cryopreservation technology to solve the organ procurement and matching problem. Cryopreservation is already essential to modern medicine — powering IVF and life-saving stem cell therapies. Now, we’re extending this technology to whole human organs — transforming hours of viability into weeks, or months, however long is necessary — so that no donated organ is lost to logistics, and no patient dies waiting. By solving this immediate need, we de-risk and build the foundation for what comes next: whole-body reversible cryopreservation. We're pausing molecular motion to give patients a bridge to future cures.

Private companySeries A
HQSan Francisco, United States
Size51–200 employees
Unlock human wisdom
ThesisTermsPrivacy
Industry
Biotechnology Research
Funding
  • Series A · $58M · Sep 22, 2025

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