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Role description

Computational Biologist - Protein Engineering

Tamarind Bio logoTamarind BioYC W24
AI-native
TypeFull-time
SponsorshipNo visa sponsorship
Salary$150,000–$250,000
LocationSan Francisco, CA
Research

We’re looking for a computational biologist to help us curate, build, and scale a comprehensive set of drug discovery tools. You will work directly with the founders to build and deploy tools for structure prediction, protein design, docking, scoring, and more. You’ll be working directly with customers to help them leverage the best open source software for their task, often chaining multiple tools together. We’re looking for someone excited about the latest advancements in AI drug discovery and both breadth and depth of knowledge in the field. 

Qualifications and Skills

  • Knowledge of ML and physics based tools in structural biology, protein design, molecular dynamics, protein-protein and protein-ligand docking, peptide discovery, virtual screening, etc.
  • Knowledge of enzymology, protein therapeutics, and peptide discovery.
  • Familiarity with literature and evolving state of the art in computational protein engineering tools
  • AWS DevOps (DynamoDB, EC2, S3, docker, etc.) and MLOps (CUDA, conda, TensorFlow, PyTorch)
  • Ability to develop general purpose, production-ready software
  • Located in the SF Bay Area or able to relocate to the Bay Area

Pluses:

  • Experience developing machine learning models for proteins (language models, structure prediction, design)
  • Knowledge of full stack software engineering, e.g. React and API development
  • Computational chemistry, including molecular dynamics, docking, and virtual screening methodologies for small molecule discovery
  • Graduate degree in math, CS, stats, bioengineering, comp bio, or a related field

Relevant archetypes

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Company info

Tamarind Bio logo

Tamarind Bio

At Tamarind(https://www.tamarind.bio), we provide web interfaces and APIs for the leading publicly available molecular design tools. Users can run models like AlphaFold/Chai-1, RFdiffusion, ProteinMPNN and 200+ others with up to hundreds of thousands of inputs running in parallel. Customers, including many top 20 biopharma, use us to design de novo binders, stabilize/solubilize antigens, improve binding affinities of protein binders, and score Abs for developability.

Private companySeries AYC W24AI-product
HQSan Francisco, United States
Size11–50 employees
Unlock human wisdom
ThesisTermsPrivacy
IndustrySoftware Development
Funding
  • Series A · $12M · Feb 24, 2026
Investors
Dimension Capital

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