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Role description

Staff Software / AI Engineer

Pathos logoPathos
Zero to oneAI-native
TypeFull-time
WorkplaceOn-site
SeniorityStaff / Lead
Salary$180,000–$200,000
LocationNew York, NY
Posted9/8/2026
Engineering

About the role

Pathos is building the first AI native biotech platform, one that turns massive multimodal datasets into foundation models, and those models into live agents that materially change how drug development is done. Instead of bolting AI onto legacy pharma systems, we are designing a new stack from the ground up.

We are hiring an engineer to architect and ship the first generation of Pathos AI and data infrastructure. Your work will power our core products and run the agents that support BD, clinical development, computational biology, and lab teams. This is an early role with broad technical scope and full ownership.

If you want to build the technical infrastructure that rewires the R&D workflow, this is the place to do your career's best work. It is one of the most direct applications of your engineering skill to advances in cancer research.

What You’ll Build

  • Build AI agents and copilots for internal teams across BD, clinical, computational biology, and lab.
  • Build robust data pipelines into a governed warehouse and knowledge graph.
  • Build MCP style servers and tooling so agents can safely talk to internal systems.
  • Work across the full product lifecycle: prototype, iterate, ship, and maintain.

Who You Are

You have architected and owned a production system end to end, from design through observability, that real users depend on. You have shipped LLM powered workflows in production, not just prototyped them. You know how technologies like LangGraph work and not just use it as a library. You make high judgment technical calls at the system level, not just execute well-scoped tasks. You move quickly, take initiative, and operate with a strong sense of ownership. You like working closely with end users and shaping products from zero to one.

Must-haves:

  • Roughly 8 or more years of professional software, ML, or product engineering experience building systems that real users depend on. We read this as a signal of demonstrated scope, not a hard gate.
  • Fluent in Python and TypeScript in production, and comfortable building full stack applications.
  • Experience with production grade APIs, eventing, and data engineering, ideally cloud native on GCP, BigQuery, or similar.
  • You own services end to end: architecture, implementation, testing, and observability.

Bonus:

  • Prior work on agentic systems at scale, retrieval systems, or ML infrastructure.
  • Experience operating in highly regulated environments that use patient and clinical trial data.

Location

This is a hybrid role, requiring 4 days per week onsite, in our NYC Headquarters.

Relevant archetypes

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Company info

Pathos logo

Pathos

AI-enabled drug development built for patients

Pathos is a clinical-stage, AI-enabled precision oncology biotech. We’re building the next generation of biopharma, where drug development is driven by AI and Multimodal patient data, not guesswork. With the largest Multimodal Foundation Model in Oncology as a backbone, we're running an integrated engine that pairs model-driven hypotheses with biological validation and biomarker-driven clinical execution, so the right therapies reach the right patients sooner.

Private companySeries DIn the news
Founded2022
HQNew York City, United States
Size11–50 employees
Unlock human wisdom
ThesisTermsPrivacy
Industry
Biotechnology Research
Funding
  • Series D · $365M · May 15, 2025
News
  • David Pesántez: Proud to Join Pathos AI as Medical Director of Clinical Development
  • AI drug firm Pathos raises $237 million, pushing valuation to $3 billion
  • BMS leads Pathos AI's $237M series E alongside Alzheimer's link-up

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