Logistics:
Director; Vice President
REMOTE
$175 - $315 /hour
6 months
10 hours/wk
ABOUT
Clora has partnered with a preclinical-stage oncology biotech that is developing antibody drug conjugates (ADCs) and radioligand therapies for the treatment of solid tumors. They are seeking an experienced translational pharmacologist to support advancement of our ADC and radioligand therapy (RLT) programs toward clinical development.
RESPONSIBILITIES
- Lead translational PK/PD strategy, integrating efficacy, biodistribution, exposure, and toxicology data.
- Develop exposure-response relationships and translational models to support clinical dose selection and therapeutic index projections.
- Guide preclinical study design, including dose optimization, scheduling, and pharmacology studies supporting IND-enabling development.
- Integrate mouse and nonhuman primate data to inform human PK projections and first-in-human dosing strategies.
- Work closely with internal scientists and external CROs to interpret results and identify critical development experiments.
IDEAL CANDIDATE
- PhD or equivalent in pharmacology, pharmaceutical sciences, or related discipline with at least 10+ industry experience within Biotech/Biopharma/Pharma organization(s)
- Demonstrated expertise in biologics PK/PD, oncology translational pharmacology, and ADC development.
- Experience with radiopharmaceuticals, dosimetry, or quantitative systems pharmacology is desirable.