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Role description

Founding Machine Learning Engineer

Synapse Social logoSynapse Social
Founding roleZero to oneAI-native
TypeFull-time
WorkplaceOn-site
LocationNew York, NY
Posted6/1/2026
Engineering

Synapse is building the world's most advanced knowledge graph for clinical research — helping cardiologists discover and connect around the latest breakthroughs. They're creating personalized feeds that surface what's most relevant, so physicians spend less time searching and more time applying cutting-edge findings.

You're joining a Google and Amazon AI startup with $600K in credits across tools, direct backing from Jeff Bezos, and connections to Amazon's leadership team. Work with an engineering leader who has shipped production models to billions of users — well de-risked with serious capital, strong connections, and enormous room to grow.

  • Founding ML Engineer role with massive upside potential. You'll own critical infrastructure from day one and work on hard technical problems at the intersection of ML, search, and knowledge graphs. Strong candidates can move through the full interview process within a week.

About this role

Along with our Founding Full-Stack Engineer, you will build:

  • Application features for our web and iOS apps
  • Intelligent ranking algorithms that surface the right paper to the right researcher at the right time
  • Semantic search & recommendation engines for vector-based systems that understand research meaning, not just keywords
  • Predictive modeling systems to forecast which research will gain momentum or shift entire fields before it happens
  • Real-time data pipelines that ingest and process millions of papers from PubMed to arXiv
  • RAG systems to break down complex papers into structured, searchable components
  • Social graph infrastructure that can build feeds, follows, and discussions that scale

Work experience

Has built and shipped 
feed ranking or graph-​based ML models 
to production

Updated

Has owned end-​to-​end data pipelines and done feature engineering for ML models.​

Updated

Experience at a VC-​backed startup,​ FAANG,​ or other company known for having a high engineering bar.​

Updated

Experience at feed-​based apps (e.​g.​,​ Instagram,​ Reddit,​ X,​ Meta,​ Pinterest,​ OpenEvidence,​ ex-​Researcher etc.​)

Education

CS or related technical degree (Bonus for PhD).​

Updated

Hard skills

Uses AI coding tools (Cursor,​ Copilot,​ etc.​) as part of daily workflow.​

Updated

Semantic search experience.​

Miscellaneous

At least one clear signal of excellence 
(e.​g.​,​ degree from a top-​tier university,​ hackathon win,​ experience at a high-​pedigree company,​ or having founded/built something impressive).​

Updated

Actively follows ML research and practitioners — knows what's current in the field.​

Relevant archetypes

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Company info

Synapse Social logo

Synapse Social

At Synapse Social, we are currently curating a high-caliber network of industry leaders and experts who are qualified to shape the discussions happening in various fields such as AI, Health, Business, and more, all within an engaging social media format.

Under 5 employees
HQNew York, US
Size3 employees
IndustrySocial Networking Platforms
Unlock human wisdom
ThesisTermsPrivacy
Tech stack
python, flask, microsoft-typescript, ios, mongodb, flatiron, react, amazon-web-services, cursor, github

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