Hot startups hiring in South San Francisco
First on the list in November 2026: Encoded Therapeutics, NewLimit and Zipline.
Latest to raise: Encoded Therapeutics, which raised $275M Series F in September 2026. Updated , using Saywise's data on startup funding and open roles. See how we rank them.
Find my matchesThe top 25, November 2026
1
Encoded Therapeutics
Encoded Therapeutics is creating one-time, disease-modifying gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective target…
Raised $275M Series F in September 2026
4 new roles in 30 days
Backed by Menlo Ventures
Investors: Menlo Ventures, Alexandria Venture Investments, Altitude Life Science Ventures, ARCH Venture Partners
11open roles$100k – $335k a year
2
NewLimit
NewLimit is a biotechnology company working to extend human healthspan by developing epigenetic reprogramming therapies.
Raised $435M Series C in June 2026
5 new roles in 30 days
Backed by Founders Fund
Investors: Founders Fund
14open roles$75k – $240k a year
3
Zipline
Zipline was founded to create the first logistics system that serves all humans equally.
Raised a Other round in August 2026
51 new roles in 30 days
Investors: Uber
267open roles$70k – $400k a year
- 4
Stripe
Help increase the GDP of the internet.
Raised a Other round in March 2026
118 new roles in 30 days
YC S09
Investors: Y Combinator, Andreessen Horowitz, Sequoia Capital, General Catalyst
475 open roles$69k – $584k a year
- 5
Neuralink
Neuralink is developing ultra-high bandwidth brain-machine interfaces to connect humans and computers.
Raised a round in May 2026
7 new roles in 30 days
Backed by Sequoia Capital
Investors: Sequoia Capital, Lightspeed Venture Partners, Founders Fund, Thrive Capital
64 open roles$59k – $281k a year
- 6
SPAN
Enabling electrification for all
Raised $163.3M Other in March 2026
12 new roles in 30 days
18 open roles$100k – $300k a year
- 7
Raised $15M Series A in August 2026
YC S23
Investors: Y Combinator, Standard Capital
6 open roles$140k – $250k a year
- 8
PerkinElmer
For 85 years, we have pushed the boundaries of science with a clear purpose – to help our customers achieve theirs.
61 new roles in 30 days
97 open roles$40k – $250k a year
- 9
Short Story
Reinventing shopping for petite women
2 new roles in 30 days
YC S19
Investors: Y Combinator
11 open roles$60k – $250k a year
- 10AE
8 new roles in 30 days
14 open roles$75k – $500k a year
- 11
7 new roles in 30 days
15 open roles$60k – $250k a year
- 12
Raised a Series C round in December 2025
1 new role in 30 days
YC W18
Investors: Y Combinator, Cultivian Sandbox Ventures, Northpond Ventures, S32
3 open roles$130k – $205k a year
- 13
Xaira Therapeutics
an integrated biotechnology company driving advances in AI to transform how we treat disease.
5 new roles in 30 days
Investors: ARCH Venture Partners, Foresite Capital
32 open roles$90k – $407k a year
- 14
Zipline
Zipline was founded to create the first logistics system that serves all humans equally.
Backed by Sequoia Capital
Investors: Sequoia Capital, Baillie Gifford, CrunchFund, Emerging Capital Partners
12 open roles$120k – $300k a year
- 15
Insitro
insitro is the physical AI company built on causal biology.
4 new roles in 30 days
Investors: Canada Pension Plan Investment Board (CPP Investments), CPP Investments
13 open roles$107k – $345k a year
- 16
Lightship
Bringing recreational vehicles into the electric age
4 new roles in 30 days
Investors: Obvious Ventures, Prelude Ventures
12 open roles$130k – $240k a year
- 17
Color
The only solution fully focused on cancer—for your full workforce.
3 new roles in 30 days
Investors: Kindred Ventures, T. Rowe Price, T. Rowe Price Associates
15 open roles$88k – $250k a year
- 18
3 new roles in 30 days
Investors: Cedar Pine, FedEx
30 open roles$75k – $300k a year
- 19
iSono Health
company in San Francisco, United States
YC W16
Investors: Y Combinator
6 open roles$70k – $205k a year
- 20
Addition Therapeutics
We're on a mission to fulfill the promise of genomic medicine for all patients.
Raised a Series A round in December 2025
1 new role in 30 days
3 open roles$78k – $98k a year
- 21SE
2 new roles in 30 days
5 open roles$100k – $380k a year
- 22
3 new roles in 30 days
4 open roles$180k – $250k a year
- 23
Phylo
Research lab studying agentic biology
Raised a Seed round in February 2026
1 new role in 30 days
4 open roles$170k – $300k a year
- 24
Frontier Medicines
Frontier Medicines is a biopharmaceutical company that “drugs the undruggable” to transform patients’ lives.
3 new roles in 30 days
3 open roles$100k – $345k a year
- 25
Cartography Biosciences
Building a smarter roadmap for precision therapeutics.
Raised a round in May 2026
1 new role in 30 days
Investors: Pfizer Venture Investments, Pfizer Ventures
3 open roles$115k – $215k a year
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